Anti-undefined Antibody BCL6,1475 Unconjugated BHA10208078

desc-alternative-names-1:(Description) Alternative Names	Bcl-6
desc-antigen-1:(Description) Antigen	B-cell lymphoma 5 protein\|B-Cell Lymphoma 6 Protein\|BCL5\|BCL6\|BCL6A\|cys his2 zinc finger transcription factor\|Lymphoma Associated Zinc Finger Gene On Chromosome 3 (LAZ3)\|Zinc finger and BTB domain-containing protein 27 (ZBTB27)\|Zinc Finger Protein 51 (ZNF51)\|zinc finger transcription factor BCL6S
desc-specificity-1:(Description) Specificity	Nuclear
prop-purity-1:(Property) Purity	3q27.3
prop-storage-1:(Property) Storage	monoclonal
prop-storage-buffer-1:(Property) Storage Buffer	Unconjugated
targ-uniprot-1	The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. Recognizes a protein of 95kDa, which is identified as Bcl-6. Antibody to bcl-6 is helpful in a number of diagnostic settings: (1) In the differential diagnosis of small B-cell lymphoma. Follicular lymphoma will show bcl-6 (and CD10) positivity whereas other small B-cell lymphomas are usually negative. (2) Bcl-6 is an important prognostic marker in diffuse large B-cell lymphomas (DLBCL), where CD10, bcl-6 and MUM1/IRF4 are used to identify germinal center and activated B-cell phenotypes. (3) Bcl-6 can be valuable in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma (NLPHL). The Reed-Sternberg cells of classical Hodgkin lymphoma are bcl-6 negative whereas the large ( L&H ) cells of NLPHL are bcl-6 positive. In contrast, anti-Bcl-6 rarely stains mantle-cell lymphoma and MALT lymphoma.
desc-host-1:{21}(Product Details) Host	Mouse
prop-purification-1:{101}(Product Details) Purification	Recombinant human bcl-6 protein fragment (around aa 256-389) (exact sequence is proprietary)
appl-tested-application-1:{73}(Product Details) Tested Application	IgG1 Kappa
desc-assay-procedure-3	Raji or Ramos cells. Tonsil
elisa-detection	Human
desc-reactivity-1	FALSE
desc-molecular-weight-1	RUO
desc-alternative-names-1	Homo Sapiens (Human)

desc-applications-8	WB
desc-categories-1	Optimal dilution for a specific application should be determined.
desc-cellular-localization-1	Western Blotting1-2μg/ml

desc-conjugate-1	P41182
desc-description-1:{15}(Description) Description	604
desc-formulation-1:{18}(Description) Formulation	BCL6, 1475
immunogen-region	BCL6
desc-intended-use-1	95kDa

desc-involvement-in-disease-1	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
desc-isotype-1:{29}(Description) Isotype	1.0mg/ml
instructions-for-use	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
desc-net-weight-g-1	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
desc-positive-control-1	Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.