This MAb recognizes TGF beta 1, 2 and 3. Three TGFĪ �s have been identified in mammals. TGFĪ �1, TGFĪ �2 and TGFĪ �3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules. Biologically active TGFĪ � requires dimerization of the monomers (usually homodimers) and release of the latent peptide portion. Overall, the mature region of the TGFĪ �3 protein has approximately 80% identity to the mature region of both TGFĪ �1 and TGFĪ �2. However, the NH2 terminals or precursor regions of their molecules share only 27% sequence identity. TGFĪ �’s inhibit the growth of epithelial cells and stimulate the growth of mesenchymal cells.Ā
Cytokine Neutralization (Order Ab without BSA/Azide); Functional Assay (Order Ab without BSA/Azide); Optimal dilution for a specific application should be determined.
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NeutFunctional Assay
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P01137; P10600; P61812
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645227
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7040;7042;7043
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200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
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1.0mg/ml
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There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
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Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Reviews of Anti-TGF-beta (Transforming Growth Factor beta) Antibody BHA10205275