Enter to Debug Area Anti-Rb1 (Tumor Suppressor Protein) Antibody BHA10204638

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Anti-Rb1 (Tumor Suppressor Protein) Antibody BHA10204638

SKU : BHA10204638

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NeoBiotechnologies, Inc.

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desc-alternative-names-1:(Description) Alternative Names	Rb1 (Tumor Suppressor Protein)
desc-antigen-1:(Description) Antigen	OSRC\|Osteosarcoma\|p105-Rb\|PP105\|pp110\|pRb\|Prepro retinoblastoma associated protein\|RB1\|Retinoblastoma 1\|Retinoblastoma-associated protein
desc-specificity-1:(Description) Specificity	Nuclear
prop-purity-1:(Property) Purity	13q14.2
prop-storage-1:(Property) Storage	monoclonal
targ-uniprot-1	Recognizes a 105kDa phosphoprotein, identified as retinoblastoma (Rb) gene product. Its epitope is localized between aa 703-772. It shows no cross reaction with p107 or p130. It specifically stains the nuclei of BT-20 cells and primary human foreskin fibroblast (HFF) cells. It does not stain the Rb-negative BT549 cells. It reacts with the hyperphosphorylated as well as the un (under) phosphorylated form of the Rb protein. Retinoblastoma gene product plays a key role in cell cycle control. It has been identified as a tumor suppressor gene whose loss of its function leads to tumor development. It is widely expressed in a variety of human tissues including breast, esophageal, squamous cell and cervical carcinoma.
desc-host-1:{21}(Product Details) Host	Mouse
prop-purification-1:{101}(Product Details) Purification	Recombinant human Rb1 protein fragment of 283 amino acid residues (exact sequence is proprietary)
appl-tested-application-1:{73}(Product Details) Tested Application	IgG1 Kappa
desc-assay-procedure-3	HeLa, A431 or BT-20 cells. Breast or Colon carcinoma.
elisa-detection	Human, Mouse
desc-reactivity-1	FALSE
desc-molecular-weight-1	RUO

desc-applications-8	WB, IHC-F, IP
desc-categories-1	(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
desc-cellular-localization-1	WB0.5-1μg/mlIP0.5-1 �g/500ug protein lysateIHC-F1-2μg/ml for 30 minutes at RT

desc-conjugate-1	P06400
desc-constituent-1	408528
desc-description-1:{15}(Description) Description	5925

desc-involvement-in-disease-1	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
desc-isotype-1:{29}(Description) Isotype	200µg/ml
instructions-for-use	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
desc-net-weight-g-1	Purified Ab with BSA and Azide at 200μg/ml

desc-recombinant-1	Download
desc-recommended-dilution-1	https://www.neobiotechnologies.com/html2pdf/pdf_create.php?cat_no=5925-MSM1X-P0
desc-regulatory-1	(pdf)

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SKU	Supplier No.	Size	Your price	Quantity
BHA10204638		20µg	$204.67		Add to Cart
BHA10204638		100µg	$393.20		Add to Cart

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