Enter to Debug Area Anti-Rb Antibody (RbS807S811-D9) Unconjugated BHA10600111

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Home / Primary Antibodies / Phospho Antibodies

Anti-Rb Antibody (RbS807S811-D9) Unconjugated BHA10600111

SKU : BHA10600111

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Abwiz Bio Inc.

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Mfr.No.	2051
desc-alternative-names-1:(Description) Alternative Names	Rb
prop-storage-1:(Property) Storage	monoclonal
prop-storage-buffer-1:(Property) Storage Buffer	Unconjugated
targ-uniprot-1	Retinoblastoma protein (Rb, phospho Rb) is a tumor suppressor protein that is inactivated in a numbr of diverse cancers. The antiproliferative activity of Rb is mediated by its ability to inhibit the transcription of genes that are required for cell cycle progression. Rb contains conserved sites that are phosphorylated by cyclin-dependent kinases (CDKs). CDK phosphorylation typically promotes protein-protien interations through creation of a phospho-epitope that becomes structured upon binding its target. However Rb phosphorylation distrupts interactions with its binding partners. When it is phosphorylated, phospho Rb is inactivated and allows execcisve cell growth that is seen in cancer cells. Sixteen potential sites for CDK-mediated phosphorylation exist in Rb and twelve of these sites have been shown to be phosphorylated in vivo.
desc-host-1:{21}(Product Details) Host	Mouse
prop-purification-1:{101}(Product Details) Purification	A synthetic phospho-peptide corresponding to residues surrounding Ser807/Ser811 of human phospho Rb
appl-tested-application-1:{73}(Product Details) Tested Application	IgG1 Kappa
standard-form	phospho-Ser807/Ser811
elisa-detection	Mouse, Human
desc-sample-type-3	RUO

desc-applications-8	WB, FACS

desc-formulation-1:{18}(Description) Formulation	RbS807S811-D9

desc-involvement-in-disease-1	1X PBS, 0.02% NaN3, 50% Glycerol, 0.1% BSA
desc-isotype-1:{29}(Description) Isotype	0.5mg/ml
biological-activity	1.0 - 0.1 µg/ml
desc-positive-control-1	-20ºC

desc-recombinant-1	Datasheet
desc-recommended-dilution-1	https://www.abwizbio.com/datasheet/datasheet.php?sku=2051
desc-regulatory-1	(pdf)

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SKU	Supplier No.	Size	Your price	Quantity
BHA10600111	2051	200µl	$466.50		Add to Cart
BHA10600111	2051	20µl	$196.67		Add to Cart

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