Enter to Debug Area Anti-p38 MAPK Antibody (P38T180Y182-E3) APC BHA10600090

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Home / Primary Antibodies / Phospho Antibodies

Anti-p38 MAPK Antibody (P38T180Y182-E3) APC BHA10600090

SKU : BHA10600090

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Abwiz Bio Inc.

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Mfr.No.	1159
desc-alternative-names-1:(Description) Alternative Names	p38 MAPK
prop-storage-1:(Property) Storage	monoclonal
prop-storage-buffer-1:(Property) Storage Buffer	APC
targ-uniprot-1	p38 mitogen-activated protein kinase (MAPK) participates in a signaling cascade that controls cellular responses to stress signals and cytokines (1). p38 MAPK isoforms p38α, p38β, p38γ (also known as Erk6 or SAPK3), and p38δ (also known as SAPK4) have been identified. p38 MAPK activation signal include inflammatory cytokines, UV light, osmotic shock, lipopolysaccharide (LPS), and growth factors (1). MKK3, MKK6, and SEK all activate p38 MAPK by phosphorylation at Thr180 and Tyr182. phospho-p38 MAPK has been shown to phosphorylate and activate MAPKAPK-2 (2) and to phosphorylate the transcription factors ATF-2 and MEF2 (3). A selective inhibitor of phospho-p38 MAPK is SB203580 (4-(4-fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)-imidazole), which inhibits the MAPKAPK-2 activation by p38 MAPK and subsequent phosphorylation of HSP27 (4). SB203580 inhibits p38 MAPK catalytic activity by binding the ATP-binding pocket, but does not inhibit p38 MAPK phosphorylation by upstream kinases (5).
desc-host-1:{21}(Product Details) Host	Mouse
prop-purification-1:{101}(Product Details) Purification	A synthetic phospho-peptide corresponding to residues surrounding Thr180/Tyr182 of human phospho p38 MAPK.
appl-tested-application-1:{73}(Product Details) Tested Application	IgG1 Kappa
standard-form	Phospho-Thr180, Phospho-Tyr182
elisa-detection	Human, Mouse, Rat
desc-sample-type-3	RUO

desc-applications-8	FACS

desc-formulation-1:{18}(Description) Formulation	P38T180Y182-E3

desc-involvement-in-disease-1	1X PBS, 0.02% NaN3, 50% Glycerol, 0.1% BSA
desc-isotype-1:{29}(Description) Isotype	0.5mg/ml
biological-activity	1.0 - 0.1 µg/ml
desc-positive-control-1	-20ºC

desc-recombinant-1	Datasheet
desc-recommended-dilution-1	https://www.abwizbio.com/datasheet/datasheet.php?sku=1159
desc-regulatory-1	(pdf)

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SKU	Supplier No.	Size	Your price	Quantity
BHA10600090	1159	100Tests	$320.67		Add to Cart
BHA10600090	1159	10Tests	$120.67		Add to Cart

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