Anti-MKK3/MKK6 Antibody (MKK3S189MKK6S207-D3) Unconjugated BHA10600083

Mfr.No.	2241
desc-alternative-names-1:(Description) Alternative Names	MKK3/MKK6
prop-storage-1:(Property) Storage	monoclonal
prop-storage-buffer-1:(Property) Storage Buffer	Unconjugated
targ-uniprot-1	MKK3 and MKK6 are closely related dual-specificity protein kinases that activate p38 MAP kinase (1-5). Phospho MKK3 and phospho MKK6 both phosphorylate and activate p38. p38 phosphorylation dramatically stimulates its ability to phosphorylate protein substrates such as ATF-2 and Elk-1. MKK3 and MKK6 are both activated by different forms of cellular stress and inflammatory cytokines (4,5). Phospho MKK3 and phospho MKK6 activation occurs through phosphorylation at S189 and T222 on MKK3 (2) and S207 and T211 on MKK6 (4,5).
desc-host-1:{21}(Product Details) Host	Mouse
prop-purification-1:{101}(Product Details) Purification	A synthetic phospho-peptide corresponding to residues surrounding Ser189 of human phospho MKK3 and Ser207 of human phospho MKK6.
appl-tested-application-1:{73}(Product Details) Tested Application	IgG1 Kappa
standard-form	Phospho-Ser189, Phospho-Ser207
elisa-detection	Mouse, Human
desc-sample-type-3	RUO

desc-applications-8	WB, FACS

desc-formulation-1:{18}(Description) Formulation	MKK3S189MKK6S207-D3

desc-involvement-in-disease-1	1X PBS, 0.02% NaN3, 50% Glycerol, 0.1% BSA
desc-isotype-1:{29}(Description) Isotype	0.5mg/ml
biological-activity	1.0 - 0.1 µg/ml
desc-positive-control-1	-20ºC