desc-alternative-names-1:(Description) Alternative Names
IgA Secretory Component / ECM1
desc-antigen-1:(Description) Antigen
ECM1, Extracellular Matrix Protein 1, Secretory Component p85, URBWD
desc-specificity-1:(Description) Specificity
Cell Surface, Cytoplasmic
prop-purity-1:(Property) Purity
1q21.2
prop-storage-1:(Property) Storage
monoclonal
targ-uniprot-1
This MAb reacts with a reduction-resistant epitope present in both free and SIgA bound Secretory Component. It does not react with the cell lines lacking secretory component. The antibody is useful for studying the distribution and level of both free and bound secretory component. Secretory component is differentially expressed in epithelium, and the antibody is a popular marker for identifying subpopulations of epithelial cells and epithelial differentiation. The Secretory component antibody is a useful research tool for studying mucosal immunity, inflammation, remodeling, differentiation and tumorigenesis, all processes associated with differential secretory component expression.
(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined.
desc-cellular-localization-1
FACS0.5-1μg/million cells in 0.1mlIF1-2μg/mlIHC-F0.5-1μg/ml for 30 minutes at RT
desc-conjugate-1
Q16610
desc-constituent-1
81071
desc-description-1:{15}(Description) Description
1893
desc-involvement-in-disease-1
200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
desc-isotype-1:{29}(Description) Isotype
1.0mg/ml
instructions-for-use
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
desc-net-weight-g-1
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Reviews of Anti-IgA Secretory Component / ECM1 Antibody BHA10200865