Enter to Debug Area Anti-EGFR Antibody (EGFRY1068-E5) FITC BHA10600050

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Home / Primary Antibodies / Phospho Antibodies

Anti-EGFR Antibody (EGFRY1068-E5) FITC BHA10600050

SKU : BHA10600050

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Abwiz Bio Inc.

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Mfr.No.	2083
desc-alternative-names-1:(Description) Alternative Names	EGFR
prop-storage-1:(Property) Storage	monoclonal
prop-storage-buffer-1:(Property) Storage Buffer	FITC
targ-uniprot-1	The epidermal growth factor (EGFR, phospho EGFR), also known as ErbB1 and HER1, is a receptor tyrosine kinase (RTK) and a known oncogenic driver of several cancer types including lung cancer (1), breast cancer (2), and glioblastoma (3) and inhibitors of EGFR have been the most successful examples of targeted therapies including antibody therapeutics (e.g. trastuzumab and cetuximab) as well as small-molecule inhibitors erlotinib and lapatinib (4). Ligand binding induces multiple EGFR auto-phosphorylation including Tyr1068. This phosphorylation recruits growth factor receptor-bound protein 2 (Grb2) which mediates downstream modulation of EGFR signaling including activation of signaling cascades through interaction of Grb2 SH3 domains with the Ras guanine exchange factor, son of sevenless homolog (SOS) or downregulation of phospho EGFR signaling through internalization and ubiquitination-targeted degradation (5).
desc-host-1:{21}(Product Details) Host	Mouse
prop-purification-1:{101}(Product Details) Purification	A synthetic phospho-peptide corresponding to residues surrounding Tyr1068 of human phospho EGFR.
appl-tested-application-1:{73}(Product Details) Tested Application	IgG1 Kappa
standard-form	phospho-Tyr1068
elisa-detection	Human, Mouse
desc-sample-type-3	RUO

desc-applications-8	FACS

desc-formulation-1:{18}(Description) Formulation	EGFRY1068-E5

desc-involvement-in-disease-1	1X PBS, 0.09% NaN3, 0.2% BSA
desc-positive-control-1	2-8ºC

desc-recombinant-1	Datasheet
desc-recommended-dilution-1	https://www.abwizbio.com/datasheet/datasheet.php?sku=2083
desc-regulatory-1	(pdf)

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SKU	Supplier No.	Size	Your price	Quantity
BHA10600050	2083	100Tests	$320.67		Add to Cart
BHA10600050	2083	10Tests	$120.67		Add to Cart

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