Epstein-Barr virus (EBV), also designated human herpesvirus 4 (HHV-4), is a member of the herpesvirus family and is one of the most common human viruses. EBV infects B cells and, though often asymptomatic, it can cause infectious mononucleosis, a disease characterized by fatigue, fever, sore throat and muscle soreness. The EBV-induced early antigens (Ea) are among several antigen complexes that have been identified in EBV-infected cells. The Ea complex is composed of diffuse (Ea-D) and restricted (Ea-R) components. The activity of Ea-D is suppressed during latent infection. BMRF1, the gene that encodes for Ea-D, is closely associated with the gene encoding for EBV DNA polymerase, and Ea-D is essential for the activity of this polymerase. Ea-D forms a complex with EBV DNase and, together, they may play a role in viral replication.
Affinity purified early antigen polypeptides from induced Raji cells precipitated with African Burkitt’s lymphoma sera
desc-assay-procedure-3
EBV-infected cells or tissues
elisa-detection
EBV
desc-reactivity-1
FALSE
desc-molecular-weight-1
RUO
desc-applications-8
IF
desc-categories-1
Optimal dilution for a specific application should be determined.
desc-cellular-localization-1
IF0.5-1μg/ml
desc-conjugate-1
Not Applicable
desc-constituent-1
Not Applicable
desc-description-1:{15}(Description) Description
Not Applicable
desc-involvement-in-disease-1
200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA; azide at 1.0mg/ml.
desc-isotype-1:{29}(Description) Isotype
1.0mg/ml
instructions-for-use
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
desc-net-weight-g-1
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Reviews of Anti-EBV Early Antigens (Epstein Barr Virus Ea) Antibody BHA10207049