Enter to Debug Area Anti-CD32 (Fc Gamma RIIa) Antibody BHA10201071

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Anti-CD32 (Fc Gamma RIIa) Antibody BHA10201071

SKU : BHA10201071

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NeoBiotechnologies, Inc.

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desc-alternative-names-1:(Description) Alternative Names	CD32 (Fc Gamma RIIa)
desc-antigen-1:(Description) Antigen	CD32A\|Fc fragment of IgG low affinity IIa receptor\|Fc gamma RIIa\|Fc-gamma RII-a\|Fc-gamma-RIIa\|FCGR2A\|FcgRII\|Fcr-2\|FcRII-a\|IGFR2
desc-specificity-1:(Description) Specificity	Cell Surface
prop-purity-1:(Property) Purity	1q23
prop-storage-1:(Property) Storage	monoclonal
targ-uniprot-1	This MAb reacts with a CD32 (FcgRII) epitope (cluster-4). It displays a stronger reaction with Daudi than with U937 cells. The epitope is located in domain 2 of FcgRIIa. Its Fab'2 fragments block immune complex binding. CD32 (Fc?RII) is a type 1 transmembrane glycoprotein that mediates several functions including phagocytosis, cytotoxicity, and immunomodulation as well as platelet aggregation. Three genes (A, B, and C) encode CD32 and at least 6 isoforms are generated via alternative mRNA splicing, i.e., IIa1, IIa2, IIb1, IIb2, IIb3 and IIc. Monocytes/macrophages, placental trophoblasts and endothelial cells express all isoforms. In addition, the IIb isoform is expressed by B cells, and the IIa isoform by platelets, granulocytes and, weakly, by B cells. NK cells and neutrophils express Isoform IIc. CD32 binds weakly to the Fc region of monomeric IgG but more strongly to IgG aggregates and immune complexes.
desc-host-1:{21}(Product Details) Host	Mouse
prop-purification-1:{101}(Product Details) Purification	K562 and FcgRII+L cells
appl-tested-application-1:{73}(Product Details) Tested Application	IgG1 Kappa
desc-assay-procedure-3	K-562 cells. Lymph node, tonsil and placenta.
elisa-detection	Human
desc-reactivity-1	FALSE
desc-molecular-weight-1	RUO

desc-applications-8	FACS, IF
desc-categories-1	Functional Studies (Order Ab without BSA & Azide); Optimal dilution for a specific application should be determined.
desc-cellular-localization-1	FACS0.5-1μg/million cells in 0.1mlIF0.5-1μg/ml

desc-conjugate-1	P12318
desc-constituent-1	352642
desc-description-1:{15}(Description) Description	2212

desc-involvement-in-disease-1	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA; azide at 1.0mg/ml.
desc-isotype-1:{29}(Description) Isotype	1.0mg/ml
instructions-for-use	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
desc-net-weight-g-1	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

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SKU	Supplier No.	Size	Your price	Quantity
BHA10201071		100µg	$393.20		Add to Cart

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