Enter to Debug Area Anti-Stat1 Antibody (Stat1S727-C6) APC BHA10600137

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Home / Primary Antibodies / Phospho Antibodies

Anti-Stat1 Antibody (Stat1S727-C6) APC BHA10600137

SKU : BHA10600137

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Abwiz Bio Inc.

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Mfr.No.	2274
desc-alternative-names-1:(Description) Alternative Names	STAT1
prop-storage-1:(Property) Storage	monoclonal
prop-storage-buffer-1:(Property) Storage Buffer	APC
targ-uniprot-1	Stat1 is a signal transducer and transcription activator that mediates cellular responses to interferons (IFNs), cytokine KITLG/SCF and other cytokines and other growth factors. Following type I IFN (IFN-alpha and IFN-beta) binding to cell surface receptors, signaling via protein kinases leads to activation of Jak kinases (TYK2 and JAK1) and to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize and associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of IFN-stimulated genes (ISG), which drive the cell in an antiviral state. In response to type II IFN (IFN-gamma), phospho Stat1 is tyrosine- and serine-phosphorylated. It then forms a homodimer termed IFN-gamma-activated factor (GAF), migrates into the nucleus and binds to the IFN gamma activated sequence (GAS) to drive the expression of the target genes, inducing a cellular antiviral state. Phospho Stat1 becomes activated in response to KITLG/SCF and KIT signaling and may mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4.
desc-host-1:{21}(Product Details) Host	Mouse
prop-purification-1:{101}(Product Details) Purification	A synthetic phospho-peptide corresponding to residues surrounding Ser727 of human phospho Stat1
appl-tested-application-1:{73}(Product Details) Tested Application	IgG1 Kappa
standard-form	phospho-Ser727
elisa-detection	Human
desc-sample-type-3	RUO

desc-applications-8	FACS

desc-formulation-1:{18}(Description) Formulation	Stat1S727-C6

desc-involvement-in-disease-1	1X PBS, 0.09% NaN3, 0.2% BSA
desc-positive-control-1	2-8ºC

desc-recombinant-1	Datasheet
desc-recommended-dilution-1	https://www.abwizbio.com/datasheet/datasheet.php?sku=2274
desc-regulatory-1	(pdf)

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SKU	Supplier No.	Size	Your price	Quantity
BHA10600137	2274	100Tests	$320.67		Add to Cart
BHA10600137	2274	10Tests	$120.67		Add to Cart

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