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UBB Antibody

SKU : BHA10557333

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desc-alternative-names-1:(Description) Alternative Names	UBB
desc-antigen-1:(Description) Antigen	UBB; FLJ25987;MGC8385;Ubiquitin B
targ-uniprot-1	Ubiquitin can be covalently linked to many cellular proteins by the ubiquitination process, which targets proteins for degradation by the 26S proteasome. Three components are involved in the target protein-ubiquitin conjugation process. Ubiquitin is first activated by forming a thiolester complex with the ubiquitin-activating enzyme (UBE1 or E1). The activated ubiquitin is subsequently transferred to the ubiquitin-carrier protein E2, and then from E2 to ubiquitin ligase E3 for final delivery to the ε-amino group of the target protein lysine residue. Combinatorial interactions of different E2 and E3 proteins result in substrate specificity. UBE1 has two isofoms: UBE1a is a nuclear protein of 117 kDa while UBE1b is a nuclear and cytoplasmic protein of 110 kDa.
desc-host-1:{21}(Product Details) Host	Mouse
desc-isotype-1:{29}(Product Details) Isotype	For research use only. Not for human, diagnostic or therapeutic use.
appl-tested-application-1:{73}(Product Details) Tested Application	IgG
prop-storage-1:{106}(Product Details) Storage	Rabbit
elisa-detection	Human, Mouse, Rat
desc-molecular-weight-1	RUO
uniprot-enrty-name	Ubiquitin can be covalently linked to many cellular proteins by the ubiquitination process, which targets proteins for degradation by the 26S proteasome. Three components are involved in the target protein-ubiquitin conjugation process. Ubiquitin is first activated by forming a thiolester complex with the ubiquitin-activating enzyme (UBE1 or E1). The activated ubiquitin is subsequently transferred to the ubiquitin-carrier protein E2, and then from E2 to ubiquitin ligase E3 for final delivery to the ε-amino group of the target protein lysine residue. Combinatorial interactions of different E2 and E3 proteins result in substrate specificity. UBE1 has two isofoms: UBE1a is a nuclear protein of 117 kDa while UBE1b is a nuclear and cytoplasmic protein of 110 kDa.
desc-description-1:{15}(Product Details) Description	100μl(100μg)
desc-alternative-names-1	Homo Sapiens (Human)

desc-applications-8	FC, ICC, WB, ELISA, IHC
desc-cellular-localization-1	WB1:1000-1:2000IHC1:100-1:200ICC1:100-1:200FC1:50-1:200
desc-chromosome-location-1	ELISA,WB,IHC,ICC,FC;WB:1:1000-1:2000,IHC:1:100-1:200,ICC:1:100-1:200,FC:1:50-1:200

desc-constituent-1	P0CG47
desc-function-1	HGNC:12463OMIM:191339KEGG:hsa:7314STRING:9606.ENSP00000304697UniGene:Hs.356190
desc-hgnc-1	Ubiquitin
desc-host-1	Endocytosis
desc-gross-weight-kg-1	Ubiquitin family
desc-immunogen-1	Ubiquitin: Cytoplasm, Nucleus

desc-involvement-in-disease-1	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
desc-mgi-1	liquid
desc-molecular-weight-1:{32}(Description) Molecular Weight	Affinity purification
desc-net-weight-g-1	Affinity purification
desc-positive-control-1	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
desc-precautions-1	Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

desc-recombinant-1	Datasheet
desc-recommended-dilution-1	https://www.cusabio.com/datasheet/158173/
desc-regulatory-1	(pdf)

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SKU	Supplier No.	Size	Your price	Quantity
BHA10557333		100μl	$387.33		Add to Cart

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