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Home / Antibodies

SERPINC1 Antibody

BHA10557227
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desc-applications-8 ELISA, WB, IHC
desc-cellular-localization-1 WB1:500-1:2000IHC1:50-1:200
desc-chromosome-location-1 ELISA,WB,IHC;WB:1:500-1:2000,IHC:1:50-1:200
desc-clonality-1:{11}(Description) Clonality 1307404
cross-reactivity This protein is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.
desc-constituent-1 P01008
desc-description-1:{15}(Description) Description 462
desc-function-1 HGNC:775OMIM:107300KEGG:hsa:462STRING:9606.ENSP00000356671UniGene:Hs.75599
desc-hgnc-1 Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin.
desc-host-1 Complement and coagulation cascades
desc-gross-weight-kg-1 Serpin family
desc-immunogen-1 Secreted, extracellular space
desc-immunogen-sequence-1 Found in plasma.
desc-intended-use-1 52,602 Da
desc-involvement-in-disease-1 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
desc-mgi-1 liquid
desc-molecular-weight-1:{32}(Description) Molecular Weight Affinity purification
desc-net-weight-g-1 Affinity purification
desc-positive-control-1 Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
desc-precautions-1 Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
desc-recombinant-1 Datasheet
desc-recommended-dilution-1 https://www.cusabio.com/datasheet/1035635/
desc-regulatory-1 (pdf)
SKU Supplier No. Size Your price Quantity
BHA10557227 100μl $387.33
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