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DEFB121 Antibody

SKU : BHA10557182

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cusabio

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desc-alternative-names-1:(Description) Alternative Names	DEFB121
desc-antigen-1:(Description) Antigen	DEFB121; ESC42RELC
targ-uniprot-1	∫-defensins (also designated BDs, or hBDs in human) are small cationic peptides with broad-spectrum antimicrobial activity against a variety of enveloped viruses, fungi and bacteria. Produced in mucosal epithelia and neutrophils of several species, ∫-defensins are developmentally regulated. The family of ∫-defensin proteins share a common defensin-motif that is characterized by multiple cysteine residues and a highly conserved tertiary structure. Besides playing a significant role in host immune defense, many ∫-defensins also are involved in sperm maturation and capacitation. ∫-defensin 121 is a 76 amino acid secreted protein that most likely contains a signal peptide sequence that requires cleavage by proteolytic enzymes in order to become biologically active. While expressed at low levels in testis, ∫-defensin 121 is abundantly expressed in epididymal caput and corpus and, unlike other ∫-defensins, it does not appear to be regulated by androgens.
targ-kegg-3	18101
desc-host-1:{21}(Product Details) Host	Mouse
prop-purification-1:{101}(Product Details) Purification	Recombinant protein of Human DEFB121
desc-isotype-1:{29}(Product Details) Isotype	For research use only. Not for human, diagnostic or therapeutic use.
appl-tested-application-1:{73}(Product Details) Tested Application	IgG
prop-storage-1:{106}(Product Details) Storage	Rabbit
elisa-detection	Human
desc-molecular-weight-1	RUO
uniprot-enrty-name	∫-defensins (also designated BDs, or hBDs in human) are small cationic peptides with broad-spectrum antimicrobial activity against a variety of enveloped viruses, fungi and bacteria. Produced in mucosal epithelia and neutrophils of several species, ∫-defensins are developmentally regulated. The family of ∫-defensin proteins share a common defensin-motif that is characterized by multiple cysteine residues and a highly conserved tertiary structure. Besides playing a significant role in host immune defense, many ∫-defensins also are involved in sperm maturation and capacitation. ∫-defensin 121 is a 76 amino acid secreted protein that most likely contains a signal peptide sequence that requires cleavage by proteolytic enzymes in order to become biologically active. While expressed at low levels in testis, ∫-defensin 121 is abundantly expressed in epididymal caput and corpus and, unlike other ∫-defensins, it does not appear to be regulated by androgens.
desc-description-1:{15}(Product Details) Description	100μl(100μg)
desc-alternative-names-1	Homo Sapiens (Human)

desc-applications-8	ELISA, WB, IHC
desc-cellular-localization-1	WB1:500-1:2000IHC1:50-1:200
desc-chromosome-location-1	ELISA,WB,IHC;WB:1:500-1:2000,IHC:1:50-1:200

desc-constituent-1	Q5J5C9
desc-function-1	HGNC:18101OMIM:616075KEGG:hsa:245934STRING:9606.ENSP00000417128UniGene:Hs.272294
desc-hgnc-1	Has antibacterial activity.
desc-gross-weight-kg-1	Beta-defensin family
desc-immunogen-1	Secreted
desc-immunogen-sequence-1	Abundant expression in the male reproductive tract only.

desc-involvement-in-disease-1	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
desc-mgi-1	liquid
desc-molecular-weight-1:{32}(Description) Molecular Weight	Affinity purification
desc-net-weight-g-1	Affinity purification
desc-positive-control-1	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
desc-precautions-1	Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

desc-recombinant-1	Datasheet
desc-recommended-dilution-1	https://www.cusabio.com/datasheet/158021/
desc-regulatory-1	(pdf)

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SKU	Supplier No.	Size	Your price	Quantity
BHA10557182		100μl	$387.33		Add to Cart

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