Enter to Debug Area Anti-CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) Antibody BHA10200291

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Anti-CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) Antibody BHA10200291

SKU : BHA10200291

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NeoBiotechnologies, Inc.

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desc-alternative-names-1:(Description) Alternative Names	CFTR (Cystic Fibrosis Transmembrane Conductance Regulator)
desc-antigen-1:(Description) Antigen	ABC35\|ATP Binding Cassette Superfamily C Member 7 (ABCC7)\|cAMP-dependent chloride channel\|CFTR\|CFTR/MRP\|Channel conductance-controlling ATPase\|Cystic Fibrosis Transmembrane Conductance Regulator\|MRP7\|TNR CFTR
desc-specificity-1:(Description) Specificity	Cell Surface, Cytoplasmic
prop-purity-1:(Property) Purity	7q31.2
prop-storage-1:(Property) Storage	monoclonal
targ-uniprot-1	Recognizes a protein of 165-170kDa, identified as cystic fibrosis transmembrane conductance regulator (CFTR). CFTR is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (Mdr1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates. The CFTR protein is a small conductance adenosine 3',5'-cyclic monophosphate (cAMP)-activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation.
desc-host-1:{21}(Product Details) Host	Mouse
prop-purification-1:{101}(Product Details) Purification	Recombinant human CFTR fragment (aa258-385) (exact sequence is proprietary)
appl-tested-application-1:{73}(Product Details) Tested Application	IgG2b
desc-assay-procedure-3	MOLT-4 cells. Pancreas, Kidney or Placenta.
elisa-detection	Human
desc-reactivity-1	FALSE
desc-molecular-weight-1	RUO

desc-applications-8	IF, IHC-F
desc-categories-1	(Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0 for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
desc-cellular-localization-1	IF0.5-1μg/mlIHC-F1-2μg/ml for 30 minutes at RT

desc-conjugate-1	P13569
desc-constituent-1	489786, 621460, 661104
desc-description-1:{15}(Description) Description	1080

desc-involvement-in-disease-1	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
desc-isotype-1:{29}(Description) Isotype	1.0mg/ml
instructions-for-use	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
desc-net-weight-g-1	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

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SKU	Supplier No.	Size	Your price	Quantity
BHA10200291		100µg	$393.20		Add to Cart

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