desc-alternative-names-1:(Description) Alternative Names
Blood Group Antigen H Type 2 (CD173)
desc-antigen-1:(Description) Antigen
A transferase|ABO|B transferase|CD173|Fucosylglycoprotein 3-alpha-galactosyltransferase|Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase|Glycoprotein-fucosylgalactoside alpha-galactosyltransferase|Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase|Histo-blood group A transferase|Histo-blood group B transferase
desc-specificity-1:(Description) Specificity
Cell Surface
prop-purity-1:(Property) Purity
9q34.2
prop-storage-1:(Property) Storage
monoclonal
targ-uniprot-1
Recognizes the blood group H type 2 antigens, trisaccharide FucĪ �1-2GalĪ �1-4GlcNAcĪ �1 of human origin. This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity. It is expressed on endothelial cells, epithelial cells and granulocytes. Increased expression of this antigen has been observed on some tumor tissues such as gastric carcinomas, urothelial carcinomas, and colon carcinomas.
(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined.
desc-cellular-localization-1
IF0.5-1μg/mlIHC-F0.5-1.0μg/ml for 30 minutes at RT
desc-conjugate-1
P16442
desc-constituent-1
654423
desc-description-1:{15}(Description) Description
28
desc-involvement-in-disease-1
200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
desc-isotype-1:{29}(Description) Isotype
1.0mg/ml
instructions-for-use
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
desc-net-weight-g-1
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Reviews of Anti-Blood Group Antigen H Type 2 (CD173) Antibody BHA10201592