desc-alternative-names-1:(Description) Alternative Names
Cyclin A2 (S- & G2-phase Cyclin)
desc-antigen-1:(Description) Antigen
CCN1, CCNA, CCNA2, Cyclin A2
desc-specificity-1:(Description) Specificity
Nuclear, Cytoplasmic
prop-purity-1:(Property) Purity
4q27
prop-storage-1:(Property) Storage
monoclonal
prop-storage-buffer-1:(Property) Storage Buffer
Unconjugated
targ-uniprot-1
It recognizes a protein of 54kDa, which is identified as cyclin A. Its epitope is located amino acids 144-148 of human Cyclin A2. Cyclins are regulatory subunits of the cyclin-dependent kinases (cdk s) and they control transition at different specific phases of the cell cycle. The temporal expression of cyclins is tightly regulated and subsequently plays a critical role in controlling the enzymatic activity of cdk s. These cyclin/cdk complexes are essential for passage through specific stages in the cell cycle. In mammalian somatic cells, cyclin A is required for S-phase and passage through G2-phase. The D and E type cyclins regulate the passage of G1, while cyclin B is a critical regulator of mitosis. Mutation or disruption of normal cyclin A expression causes cells to arrest in G2-phase.
Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes,Optimal dilution for a specific application should be determined.
desc-cellular-localization-1
Immunohistology (Formalin-fixed)1-2μg/ml for 30 min at RT
desc-conjugate-1
P20248
desc-description-1:{15}(Description) Description
890
desc-formulation-1:{18}(Description) Formulation
CCNA2, 2333
immunogen-region
CCNA2
desc-intended-use-1
54kDa
desc-involvement-in-disease-1
200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
desc-isotype-1:{29}(Description) Isotype
1.0mg/ml
instructions-for-use
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
desc-net-weight-g-1
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
desc-positive-control-1
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
No Description Available.
No Description Available.
Reviews of Anti-undefined Antibody CCNA2,2333 Unconjugated BHA10208170