Anti-undefined Antibody BLCAM,1795 Unconjugated BHA10208109

desc-alternative-names-1:(Description) Alternative Names	CD22 / BL-CAM
desc-antigen-1:(Description) Antigen	B-lymphocyte cell adhesion molecule (BL-CAM)\|B-cell receptor CD22\|CD22\|Lectin 2\|Lyb8\|Sialic acid-binding Ig-like lectin 2 (Siglec-2)\|SIGLEC2\|T-cell surface antigen Leu-14
desc-specificity-1:(Description) Specificity	Cell Surface
prop-purity-1:(Property) Purity	19q13.1
prop-storage-1:(Property) Storage	monoclonal
prop-storage-buffer-1:(Property) Storage Buffer	Unconjugated
targ-uniprot-1	Recognizes a protein of 130-140kDa, identified as CD22 (also known as BL-CAM). CD22 expression is restricted to normal and neoplastic B cells and is absent from other haemopoietic cell types. In B-cell ontogeny, CD22 is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. It is not expressed by plasma cells, CD22 is found highly expressed in follicular mantle and marginal zone B-cells, and while germinal center B-cells are relatively weak. CD22 is a member of the immunoglobulin superfamily and serves as an adhesion receptor for sialic acid-bearing ligands expressed on erythrocytes and all leukocyte classes. It also associates with tyrosine kinases and play a role in signal transduction and B-cell activation.
desc-host-1:{21}(Product Details) Host	Mouse
prop-purification-1:{101}(Product Details) Purification	Recombinant fragment of human BL-CAM/CD22 protein (around aa 52-178) (exact sequence is proprietary)
appl-tested-application-1:{73}(Product Details) Tested Application	IgG1 Kappa
desc-assay-procedure-3	Raji, Daudi, IM9, JY25 and human peripheral blood lymphocytes. Human Tonsil, Lymph Node or Spleen.
elisa-detection	Human
desc-reactivity-1	FALSE
desc-molecular-weight-1	RUO
desc-alternative-names-1	Homo Sapiens (Human)

desc-applications-8	ELISA, IHC-F, WB
desc-categories-1	Order Ab without BSA, Order Ab without BSA, Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes,Optimal dilution for a specific application should be determined.
desc-cellular-localization-1	ELISAUse Ab at 2-4μg/ml for coatingWestern Blotting0.5-1.0μg/mlImmunohistology (Formalin-fixed)1-2μg/ml for 30 minutes at RT

desc-conjugate-1	P20273
desc-description-1:{15}(Description) Description	933
desc-formulation-1:{18}(Description) Formulation	BLCAM, 1795
immunogen-region	CD22
desc-intended-use-1	130-140kDa

desc-involvement-in-disease-1	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
desc-isotype-1:{29}(Description) Isotype	1.0mg/ml
instructions-for-use	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
desc-net-weight-g-1	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
desc-positive-control-1	Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.