desc-alternative-names-1:(Description) Alternative Names
TIMP2 (Tissue Inhibitor of Metalloproteinase 2)
desc-antigen-1:(Description) Antigen
Metalloproteinase inhibitor 2|TIMP metallopeptidase inhibitor 2|TIMP-2|TIMP2|Tissue Inhibitor of Metalloproteinase 2
desc-specificity-1:(Description) Specificity
Cell Surface, Cytoplasmic
prop-purity-1:(Property) Purity
17q25
prop-storage-1:(Property) Storage
monoclonal
targ-uniprot-1
It recognizes a protein of 21kDa, identified as tissue inhibitor of metalloproteinases-2 (TIMP-2). It is closely related to TIMP-1 and shows the highest binding affinity to both the latent (pro) and active forms of 72kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.
HeLa cells. Normal Placenta. Breast, Colon, Endometrial, Prostate or Ovarian Carcinoma.
elisa-detection
Cow, Zebrafish, Rabbit, Rat, Mouse, Human, Guinea pig
desc-reactivity-1
FALSE
desc-molecular-weight-1
RUO
desc-applications-8
IHC-F, WB, IF, FACS
desc-categories-1
(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
desc-cellular-localization-1
FACS0.5-1μg/million cellsIF0.5-1μg/mlWB0.5-1μg/mlIHC-F1-2μg/ml for 30 minutes at RT
desc-conjugate-1
P16035
desc-constituent-1
633514
desc-description-1:{15}(Description) Description
7077
desc-involvement-in-disease-1
200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
desc-isotype-1:{29}(Description) Isotype
1.0mg/ml
instructions-for-use
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
desc-net-weight-g-1
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Reviews of Anti-TIMP2 (Tissue Inhibitor of Metalloproteinase 2) Antibody BHA10205322