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Home / Antibodies

Anti-SUMO-2 Antibody BHA10204975

SKU : BHA10204975

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NeoBiotechnologies, Inc.

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desc-alternative-names-1:(Description) Alternative Names	SUMO-2
desc-antigen-1:(Description) Antigen	HSMT3\|Sentrin 2\|Small ubiquitin like modifier 2\|Small ubiquitin like modifier protein 3\|SMT3A\|SMT3B\|SMT3 homolog 1 (SMT3H1)\|SMT3 homolog 2 (SMT3H2)\|SMT3 homolog\|SMT3 suppressor of mif two 3 homolog 1
desc-specificity-1:(Description) Specificity	Nuclear
prop-purity-1:(Property) Purity	17q25.1
prop-storage-1:(Property) Storage	monoclonal
targ-uniprot-1	The small ubiquitin-related modifier (SUMO) proteins, which include SUMO-1, 2 and 3, belong to the ubiquitin-like protein family. Like ubiquitin, the SUMO proteins are synthesized as precursor proteins that undergo processing before conjugation to target proteins. Also, both utilize the E1, E2 and E3 cascade enzymes for conjugation. However, SUMO and ubiquitin differ with respect to targeting. Ubiquitination predominantly targets proteins for degradation, whereas sumoylation targets proteins to a variety of cellular processing, including nuclear transport, transcriptional regulation, apoptosis and protein stability. The unconjugated SUMO-1, 2 and 3 proteins localize to the nuclear membrane, nuclear bodies and cytoplasm, respectively. SUMO-1 utilizes Ubc9 for conjugation to several target proteins, which include MDM2, p53, PML and RanGap1. SUMO-2 and 3 contribute to a greater percentage of protein modification than does SUMO-1 and unlike SUMO-1, they can form polymeric chains. In addition, SUMO-3 regulates beta-Amyloid generation and may be critical in the onset or progression of Alzheimer s disease.
desc-host-1:{21}(Product Details) Host	Mouse
prop-purification-1:{101}(Product Details) Purification	Recombinant human SUMO2 protein
appl-tested-application-1:{73}(Product Details) Tested Application	IgG1 Kappa
desc-assay-procedure-3	HeLa cells or breast carcinoma
elisa-detection	Human, Rat
desc-reactivity-1	FALSE
desc-molecular-weight-1	RUO

desc-applications-8	FACS, IF, IHC-F
desc-categories-1	(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined.
desc-cellular-localization-1	FACS0.5-1μg/million cells in 0.1mlIF0.5-1μg/mlIHC-F0.5-1μg/ml for 30 minutes at RT

desc-conjugate-1	P55854
desc-constituent-1	474005
desc-description-1:{15}(Description) Description	6613

desc-involvement-in-disease-1	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
desc-isotype-1:{29}(Description) Isotype	1.0mg/ml
instructions-for-use	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
desc-net-weight-g-1	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

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SKU	Supplier No.	Size	Your price	Quantity
BHA10204975		100µg	$393.20		Add to Cart

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