Enter to Debug Area Anti-STAT3 Antibody BHA11302462

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Anti-STAT3 Antibody BHA11302462

SKU : BHA11302462

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desc-alternative-names-1:(Description) Alternative Names	STAT3
desc-antigen-1:(Description) Antigen	Signal transducer and activator of transcription 3\|Acute-phase response factor\|STAT-3\|APRF
prop-purity-1:(Property) Purity	17q21.2
prop-storage-1:(Property) Storage	polyclonal
targ-uniprot-1	Membrane receptor signaling by various ligands, including interferons and growth hormones such as EGF, induces activation of JAK kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN-α and form a heterodimer which is part of the ISGF3 transcription factor complex. Although early reports indicate Stat3 activation by EGF and IL-6, it has been shown that Stat3β appears to be activated by both while Stat3α is activated by EGF, but not by IL-6. Highest expresion of Stat4 is seen in testis and myeloid cells. IL-12 has been identified as an activator of Stat4. Stat5 has been shown to be activated by Prolactin and by IL-3. Stat6 is involved in IL-4 activated signaling pathways.
desc-host-1:{21}(Product Details) Host	Mouse
prop-purification-1:{101}(Product Details) Purification	Synthetic phosphopeptide derived from human Stat3 around the phosphorylation site of Serine 727.
standard-form	phospho-S727
elisa-detection	Human, Mouse, Rat
desc-reactivity-1	FALSE
desc-molecular-weight-1	RUO
desc-alternative-names-1	Homo Sapiens (Human)

desc-applications-8	WB, IHC, IP
desc-cellular-localization-1	WB1:500-1:1000IHC1:50-1:200IP1:50-1:200

desc-conjugate-1	P40763
desc-constituent-1	P40763
desc-intended-use-1	88 kDa

instructions-for-use	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.Specificity: p-Stat3 (S727) polyclonal antibody detects endogenous levels of Stat3 protein only when phosphorylated at Ser727.
desc-net-weight-g-1	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
desc-positive-control-1	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

desc-recombinant-1	Datasheet
desc-recommended-dilution-1	https://www.bioworlde.com/pdf/BS4180.pdf
desc-regulatory-1	(pdf)

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SKU	Supplier No.	Size	Your price	Quantity
BHA11302462		50µl	$199.33		Add to Cart
BHA11302462		100µl	$314.89		Add to Cart

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