Anti-SMAD5 Antibody BHA11308914

desc-alternative-names-1:(Description) Alternative Names	Smad5
desc-antigen-1:(Description) Antigen	Mothers against decapentaplegic homolog 5\|MAD homolog 5\|Mothers against DPP homolog 5\|JV5-1\|SMAD family member 5\|SMAD 5\|Smad5\|hSmad5\|SMAD5\|MADH5
prop-purity-1:(Property) Purity	5q31.1
prop-storage-1:(Property) Storage	monoclonal
targ-uniprot-1	Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad) have been implicated as downstream effectors of TGFβ/BMP signaling. Smad1 (also designated Madr1 or JV4-1), Smad5 and mammalian Smad8 (also designated Smad9 or MADH6) are effectors of BMP2 and BMP4 function while Smad2 (also designated Madr2 or JV18-1) and Smad3 are involved in TGFβ and activin-mediated growth modulation. Smad4 (also designated DPC4) has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGFβ signaling by interfering with TGFβ-mediated phosphorylation of other Smad family members.
desc-host-1:{21}(Product Details) Host	Mouse
prop-purification-1:{101}(Product Details) Purification	Recombinant antibody.
standard-form	phospho-S463/465
elisa-detection	Human, Mouse, Rat
desc-reactivity-1	TRUE
desc-molecular-weight-1	RUO
desc-alternative-names-1	Homo Sapiens (Human)

desc-applications-8	WB, ICC, IHC
desc-cellular-localization-1	WB1:1,000-1:2,000ICC/IHC1:50-1:200

instructions-for-use	Product: Recombinant Rabbit Monoclonal Antibody. 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.Specificity: This antibody detects endogenous levels of human Smad 5 protein only when phosphorylated at Ser463 and Ser465.
desc-net-weight-g-1	Protein A affinity purified
desc-positive-control-1	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.