Enter to Debug Area Anti-RPS6KA5 Antibody BHA11300040

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Anti-RPS6KA5 Antibody BHA11300040

SKU : BHA11300040

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desc-alternative-names-1:(Description) Alternative Names	RPS6KA5
desc-antigen-1:(Description) Antigen	Ribosomal protein S6 kinase alpha-5\|S6K-alpha-5\|90 kDa ribosomal protein S6 kinase 5\|Nuclear mitogen- and stress-activated protein kinase 1\|RSK-like protein kinase\|RSKL\|RPS6KA5\|MSK1
prop-purity-1:(Property) Purity	14q32.11
prop-storage-1:(Property) Storage	polyclonal
targ-uniprot-1	MSK-1 is a mitogen and stress activated protein kinase-1 which belongs to the AGC family of kinases and is related in structure to the ribosomal p70 S6 kinase subfamily. MSK-1can be activated by ERK1/2 and SAPK2 /p38 MAP kinase. It is also known to be required for the phosphorylation of CREB, ATF1 H3 and HMG-14 in response to mitogen and stress. Similar to RSK, MSK-1 contains two kinase domains (N-term and a C-term). Once phosphorylated on Thr581 and Ser360 by ERK1/2 and SAPK2/p38, MSK-1 autophosphorylate on at least 5 sites. Of these autophosphorylation sites Ser212 and Ser376 get phosphorylated by the C-terminal kinase domain of MSK-1 which is essential for the catalytic activity of the N-terminal kinase domain.
desc-host-1:{21}(Product Details) Host	Mouse
prop-purification-1:{101}(Product Details) Purification	Synthetic phosphopeptide derived from human MSK1 around the phosphorylation site of Serine 360.
standard-form	phospho-S360
elisa-detection	Human, Mouse, Rat
desc-reactivity-1	FALSE
desc-molecular-weight-1	RUO
desc-alternative-names-1	Homo Sapiens (Human)

desc-applications-8	WB
desc-cellular-localization-1	WB1:500-1:1000

desc-conjugate-1	O75582
desc-constituent-1	O75582
desc-intended-use-1	90 kDa

instructions-for-use	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.Specificity: MSK1 (phospho-S360) polyclonal antibody detects endogenous levels of MSK1 only when phosphorylated at Ser360.
desc-net-weight-g-1	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
desc-positive-control-1	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

desc-recombinant-1	Datasheet
desc-recommended-dilution-1	https://www.bioworlde.com/pdf/AP0286.pdf
desc-regulatory-1	(pdf)

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SKU	Supplier No.	Size	Your price	Quantity
BHA11300040		50µl	$199.33		Add to Cart
BHA11300040		100µl	$314.89		Add to Cart

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