desc-alternative-names-1:(Description) Alternative Names
Progesterone Receptor
desc-antigen-1:(Description) Antigen
NR3C3|Nuclear receptor subfamily 3 group C member 3|PGR|PR|PRA|PRB|Progesterone receptor form A|Progesterone receptor form B
desc-specificity-1:(Description) Specificity
Nucleus
prop-purity-1:(Property) Purity
11q22.1
prop-storage-1:(Property) Storage
monoclonal
targ-uniprot-1
This MAb is specific to progesterone receptor and shows minimal cross-reaction with other members of the family. Progesterone receptor is expressed as two major isoforms, PR-A (81kDa) and PR-B (116kDa). Expression of PgR has been suggested to reflect a intact estrogen regulatory machinery and therefore, predict better clinical response to endocrine therapy than ER alone. It is excellent for immunohistochemical staining of formalin/paraffin tissues.
(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined.
desc-cellular-localization-1
IHC-F0.5-1μg/ml for 30 min at RT
desc-conjugate-1
P06401
desc-constituent-1
2905
desc-description-1:{15}(Description) Description
5241
desc-involvement-in-disease-1
200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
desc-isotype-1:{29}(Description) Isotype
1.0mg/ml
instructions-for-use
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
desc-net-weight-g-1
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Reviews of Anti-Progesterone Receptor Antibody BHA10204086