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Home / Antibodies

Anti-N-Cadherin / Cadherin-2 / CD325 (NCAD) Antibody BHA10200013

SKU : BHA10200013

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NeoBiotechnologies, Inc.

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desc-alternative-names-1:(Description) Alternative Names	N-Cadherin / Cadherin-2 / CD325 (NCAD)
desc-antigen-1:(Description) Antigen	Cadherin-2 N cadherin neuronal\|Cadherin-2 type 1\|Cadherin-2\|Calcium dependent adhesion protein neuronal\|CD325\|CDH2\|CDHN\|CDw325\|N-Cadherin\|NCAD
desc-specificity-1:(Description) Specificity	Cell Surface
prop-purity-1:(Property) Purity	18q11.2
prop-storage-1:(Property) Storage	monoclonal
targ-uniprot-1	Recognizes a protein of ~140kDa, identified as N-Cadherin (NCAD), also known as CD325. N-cadherin is a 140 kDa protein belonging to a family of transmembrane molecules that mediate calcium-dependent intercellular adhesion. Cadherins are involved in controlling morphogenetic movements during development and regulate cell surface adhesion through homotypic adhesion with the same cadherin species. Expression of N-cadherin has been reported on a variety of normal tissues including neuronal, endothelial and muscle cells, and a subpopulation of early hematopoietic progenitor cells. Results aid in the classification of malignant non-carcinomatous neoplasms including mesotheliomas, chordomas, synovial sarcomas, malignant melanomas, epithelioid sarcomas, epithelioid angiosarcomas, clear cell sarcomas as well as serous and endometrioid tumors of the ovary have been demonstrated to be N-cadherin positive, whereas mucinous tumors are negative. Other N-cadherin-positive neoplasms include renal cell carcinomas and some variant breast tumors, including medullary breast carcinomas and sarcomatoid metaplastic breast carcinomas.
desc-host-1:{21}(Product Details) Host	Mouse
prop-purification-1:{101}(Product Details) Purification	Recombinant human CDH2 intracellular domain (exact sequence is proprietary)
appl-tested-application-1:{73}(Product Details) Tested Application	IgG1 Kappa
desc-assay-procedure-3	HeLa or HUVEC cells. Heart, Pancreas or Cerebral Cortex
elisa-detection	Human, Mouse
desc-reactivity-1	FALSE
desc-molecular-weight-1	RUO

desc-applications-8	FACS, WB, IHC-F
desc-categories-1	(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tis with1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
desc-cellular-localization-1	FACS0.5-1μg/million cellsWB0.5-1.0μg/mlIHC-F0.5-1.0μg/ml for 30 minutes at RT

desc-conjugate-1	P19022
desc-constituent-1	464829
desc-description-1:{15}(Description) Description	1000

desc-involvement-in-disease-1	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
desc-isotype-1:{29}(Description) Isotype	1.0mg/ml
instructions-for-use	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
desc-net-weight-g-1	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

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SKU	Supplier No.	Size	Your price	Quantity
BHA10200013		100µg	$393.20		Add to Cart

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