Enter to Debug Area Anti-MAP2K1 Antibody BHA11300014

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Anti-MAP2K1 Antibody BHA11300014

SKU : BHA11300014

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desc-alternative-names-1:(Description) Alternative Names	MAP2K1
desc-antigen-1:(Description) Antigen	Dual specificity mitogen-activated protein kinase kinase 1\|MAP kinase kinase 1\|MAPKK 1\|MKK1\|ERK activator kinase 1\|MAPK/ERK kinase 1\|MEK 1\|MAP2K1\|MEK-1\|PRKMK1
prop-purity-1:(Property) Purity	15q22.31
prop-storage-1:(Property) Storage	polyclonal
targ-uniprot-1	MEK1 (Mitogen activated protein kinase kinase 1) catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. MEK1 activates ERK1 and ERK2 MAP kinases. Mitogen activated protein kinase kinase 2 (MEK2 or MAPKK2) is a member of a family of tyrosine/threonine protein kinases that activate the ERK1 and 2 and MAPK enzymes by phosphorylating both residues within the threonine/glutamate/tyrosine (TEY) motif in the activation loop. MEK1 and 2 are also activated by dual phosphorylation, which occurs on serine 218 and 222, in the activation loop of the MEK. Threonine 292 of MEK1 is phosphorylated by ERK 2, which serves as a negative feedback loop by suppressing activation of MEK1.
desc-host-1:{21}(Product Details) Host	Mouse
prop-purification-1:{101}(Product Details) Purification	Synthetic phosphopeptide derived from human MEK1 around the phosphorylation site of Serine 298.
standard-form	phospho-S298
elisa-detection	Human, Mouse, Rat
desc-reactivity-1	FALSE
desc-molecular-weight-1	RUO
desc-alternative-names-1	Homo Sapiens (Human)

desc-applications-8	WB
desc-cellular-localization-1	WB1:500-1:1000

desc-conjugate-1	Q02750
desc-constituent-1	Q02750
desc-intended-use-1	43 kDa

instructions-for-use	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.Specificity: p-MEK1(S298) polyclonal antibody detects endogenous levels of MEK1 protein only when phosphorylated at Ser298.
desc-net-weight-g-1	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
desc-positive-control-1	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

desc-recombinant-1	Datasheet
desc-recommended-dilution-1	https://www.bioworlde.com/pdf/AP0092.pdf
desc-regulatory-1	(pdf)

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SKU	Supplier No.	Size	Your price	Quantity
BHA11300014		50µl	$199.33		Add to Cart
BHA11300014		100µl	$314.89		Add to Cart

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