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Home / Antibodies

Anti-Kappa Light Chain Antibody BHA10202242

SKU : BHA10202242

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NeoBiotechnologies, Inc.

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desc-alternative-names-1:(Description) Alternative Names	Kappa Light Chain
desc-antigen-1:(Description) Antigen	HCAK1\|Ig Kappa Chain C Region\|IGKC\|Immunoglobulin KM
desc-specificity-1:(Description) Specificity	Cell Surface, Cytoplasmic (Secreted)
prop-purity-1:(Property) Purity	2p11.2
prop-storage-1:(Property) Storage	monoclonal
targ-uniprot-1	This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. It recognizes human Ig kappa light chains of both secreted and cell surface immunoglobulin. It detects also free kappa light chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
desc-host-1:{21}(Product Details) Host	Mouse
prop-purification-1:{101}(Product Details) Purification	Human IgG-kappa myeloma protein
appl-tested-application-1:{73}(Product Details) Tested Application	IgG1 Kappa
desc-assay-procedure-3	293T, Raji or hPBL cells. Tonsil or Spleen
elisa-detection	Human
desc-reactivity-1	FALSE
desc-molecular-weight-1	RUO

desc-applications-8	FACS, IF, IHC-F
desc-categories-1	(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined.
desc-cellular-localization-1	FACS0.5-1μg/million cells in 0.1mlIF0.5-1μg/mlIHC-F0.5-1.0μg/ml for 30 min at RT

desc-conjugate-1	P01601; P01834
desc-constituent-1	449609
desc-description-1:{15}(Description) Description	3514

desc-involvement-in-disease-1	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
desc-isotype-1:{29}(Description) Isotype	1.0mg/ml
instructions-for-use	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
desc-net-weight-g-1	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

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SKU	Supplier No.	Size	Your price	Quantity
BHA10202242		100µg	$393.20		Add to Cart

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