This antibody is specific to Insulin-like Growth Factor (IGF-1) and shows minimal cross-reaction with IGF-11, Proinsulin, MSF, and Insulin. IGF-1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF-IB while isoform 2 is known as IGF-IA. IGF-1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon.
Pancreas or brain. Breast, Thyroid or Colon Cancers; IGF-1 recombinant protein
elisa-detection
Rabbit, Rat, Mouse, Human
desc-reactivity-1
FALSE
desc-molecular-weight-1
RUO
desc-applications-8
FACS, IF
desc-categories-1
In-vitro Neutralization of Biological Activity of IGF-1 . Optimal dilution for a specific application should be determined.
desc-cellular-localization-1
FACS0.5-1μg/million cells in 0.1mlIF1-2μg/ml
desc-conjugate-1
P05019
desc-constituent-1
160562
desc-description-1:{15}(Description) Description
3479
desc-involvement-in-disease-1
200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA; azide at 1.0mg/ml.
desc-isotype-1:{29}(Description) Isotype
1.0mg/ml
instructions-for-use
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
desc-net-weight-g-1
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Reviews of Anti-Insulin-like Growth Factor-1 (IGF-1) Antibody BHA10202099