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Home / Antibodies

Anti-Histone H1 Antibody BHA10201726

SKU : BHA10201726

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NeoBiotechnologies, Inc.

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desc-alternative-names-1:(Description) Alternative Names	Histone H1
desc-antigen-1:(Description) Antigen	H1(0)\|H1.1\|H1.2\|H1.3\|H1.4\|H1.5\|H10\|H1A\|H1F0\|H1F1
desc-specificity-1:(Description) Specificity	Nuclear
prop-purity-1:(Property) Purity	3q21-q22; 6q21-q22; 22q13.1
prop-storage-1:(Property) Storage	monoclonal
targ-uniprot-1	Eukaryotic histones are basic and water-soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form the octamer; formed of two H2A-H2B dimers and two H3-H4 dimers, forming two nearly symmetrical halves by tertiary structure. Over 80% of nucleosomes contain the linker Histone H1, derived from an intronless gene that interacts with linker DNA between nucleosomes and mediates compaction into higher order chromatin. Histones are subject to posttranslational modification by enzymes primarily on their N-terminal tails, but also in their globular domains. Such modifications include methylation, citrullination, acetylation, phosphorylation, sumoylation, ubiquitination and ADP-ribosylation.
desc-host-1:{21}(Product Details) Host	Mouse
prop-purification-1:{101}(Product Details) Purification	Nuclei of human leukemia biopsy cells
appl-tested-application-1:{73}(Product Details) Tested Application	IgG2a Kappa
desc-assay-procedure-3	HeLa, A-431, LNCap or Jurkat cells. Breast carcinoma.
elisa-detection	Human, Mouse, Rat
desc-reactivity-1	FALSE
desc-molecular-weight-1	RUO

desc-applications-8	FACS, IF, IHC-F
desc-categories-1	(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined.
desc-cellular-localization-1	FACS0.5-1μg/million cells in 0.1mlIF0.5-1μg/mlIHC-F0.5-1μg/ml for 30 minutes at RT

desc-conjugate-1	P07305
desc-constituent-1	226117; 97358
desc-description-1:{15}(Description) Description	3005

desc-involvement-in-disease-1	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 1mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
desc-isotype-1:{29}(Description) Isotype	1.0mg/ml
instructions-for-use	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
desc-net-weight-g-1	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

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SKU	Supplier No.	Size	Your price	Quantity
BHA10201726		100µg	$393.20		Add to Cart

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