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Home / Antibodies

Anti-GP2 (Glycoprotein 2) / ZAP75 Antibody BHA10201639

SKU : BHA10201639

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NeoBiotechnologies, Inc.

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desc-alternative-names-1:(Description) Alternative Names	GP2 (Glycoprotein 2) / ZAP75
desc-antigen-1:(Description) Antigen	Glycoprotein 2 (zymogen granule membrane)\|GP2\|Pancreatic zymogen granule membrane associated protein GP2\|Pancreatic zymogen granule membrane protein GP-2\|ZAP75
desc-specificity-1:(Description) Specificity	Cell Surface(secreted)
prop-purity-1:(Property) Purity	16p12
prop-storage-1:(Property) Storage	monoclonal
targ-uniprot-1	GP2 (glycoprotein 2), also known as ZAP75, is a 537 amino acid secreted protein. It is an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. GP2 is cleaved and then released into the pancreatic duct along with exocrine secretions. GP2 binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). GP2 is also expressed on the apical plasma membrane of specialized microfold (M) cells among enterocytes and serves as a transcytotic receptor for mucosal antigens. M cells are considered a promising target for oral vaccination against various infectious diseases.
desc-host-1:{21}(Product Details) Host	Mouse
prop-purification-1:{101}(Product Details) Purification	Recombinant human GP2 protein fragment (aa35-179) (exact sequence is proprietary)
appl-tested-application-1:{73}(Product Details) Tested Application	IgG
desc-assay-procedure-3	PANC-1 cells. Pancreas
elisa-detection	Human
desc-reactivity-1	FALSE
desc-molecular-weight-1	RUO

desc-applications-8	FACS, IF, IHC-F
desc-categories-1	(Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0 for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
desc-cellular-localization-1	FACS0.5-1μg/million cellsIF0.5-1μg/mlIHC-F1-2μg/ml for 30 minutes at RT

desc-conjugate-1	P55259
desc-constituent-1	53985
desc-description-1:{15}(Description) Description	2813

desc-involvement-in-disease-1	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
desc-isotype-1:{29}(Description) Isotype	1.0mg/ml
instructions-for-use	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
desc-net-weight-g-1	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

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SKU	Supplier No.	Size	Your price	Quantity
BHA10201639		100µg	$393.20		Add to Cart

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