desc-alternative-names-1:(Description) Alternative Names
GFAP
desc-antigen-1:(Description) Antigen
Astrocyte or Intermediate Filament Protein|Glial Fibrillary Acidic Protein
desc-specificity-1:(Description) Specificity
Cytoplasmic
prop-purity-1:(Property) Purity
17q21.31
prop-storage-1:(Property) Storage
monoclonal
targ-uniprot-1
This MAb recognizes a protein of ~50kDa which is identified as Glial Fibrillary Acidic Protein (GFAP). It shows no cross-reaction with other intermediate filament proteins. GFAP is specifically found in astroglia. GFAP is a very popular marker for localizing benign astrocyte and neoplastic cells of glial origin in the central nervous system. Antibody to GFAP is useful in differentiating primary gliomas from metastatic lesions in the brain and for documenting astrocytic differentiation in tumors outside the CNS.
(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined.
desc-cellular-localization-1
FACS0.5-1μg/million cells in 0.1mlIF1-2μg/mlWB0.5-1μg/mlIHC-F0.25-0.5μg/ml for 30 minutes at RT
desc-conjugate-1
P14136
desc-constituent-1
514227
desc-description-1:{15}(Description) Description
2670
desc-involvement-in-disease-1
200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
desc-isotype-1:{29}(Description) Isotype
1.0mg/ml
instructions-for-use
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.