desc-alternative-names-1:(Description) Alternative Names
Galectin-13 (GAL13) / Placental Protein 13 (PP13)
desc-antigen-1:(Description) Antigen
Gal-13|GAL13|Galactoside-binding soluble lectin 13|Galectin-13|Galectin13|Lectin galactoside binding soluble 13|LGALS13|PLAC8|Placental protein 13 (PP13)|Placental tissue protein 13
desc-specificity-1:(Description) Specificity
Cell Surface, Cytoplasmic
prop-storage-1:(Property) Storage
monoclonal
targ-uniprot-1
It recognizes a 32kDa protein, which is identified as homodimer of galectin-13 (also known as PP13). Galectins are a family of soluble β-galactoside-binding lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. One such member, galectin-13, is a 139 amino acid protein that contains one galectin domain. Possessing lysophospholipase activity, galectin-13 exists as a disulfide-linked homodimer. Galectin-13 is suggested to have a developmental role in the placenta and may display immunobiological activity in feto-maternal blood-spaces. Screening for galectin-13 in maternal serum during the first trimester of pregnancy may serve as a diagnostic marker to predict preterm pre-eclampsia.
(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0 or 10mM Citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
desc-cellular-localization-1
ELISAFor coating, order Ab without BSAFACS0.5-1μg/million cellsIF0.5-1μg/mlIHC-F0.5-1μg/ml for 30 minutes at RT
desc-conjugate-1
Q9UHV8
desc-constituent-1
23671 Human Gene SymbolLGALS13Hu Chromosome Location19q13.1
desc-description-1:{15}(Description) Description
29124
desc-involvement-in-disease-1
200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 1mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
desc-isotype-1:{29}(Description) Isotype
1.0mg/ml
instructions-for-use
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
desc-net-weight-g-1
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Reviews of Anti-Galectin-13 (GAL13) / Placental Protein 13 (PP13) Antibody BHA10201669