Enter to Debug Area Anti-EIF4EBP1 Antibody BHA11302674

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Home / Antibodies

Anti-EIF4EBP1 Antibody BHA11302674

SKU : BHA11302674

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desc-alternative-names-1:(Description) Alternative Names	EIF4EBP1
desc-antigen-1:(Description) Antigen	Eukaryotic translation initiation factor 4E-binding protein 1\|4E-BP1\|eIF4E-binding protein 1\|Phosphorylated heat- and acid-stable protein regulated by insulin 1\|PHAS-I\|EIF4EBP1\|4EBP1\|PHAS I\|PHASI
prop-purity-1:(Property) Purity	8p11.23
prop-storage-1:(Property) Storage	polyclonal
targ-uniprot-1	The translation of proteins from eukaryotic mRNA is initiated by the multisubunit complex eIF-4F, which associates with the mRNA 5' cap structure. eIF-4E, a component of eIF-4F, is responsible for binding to the 5' cap structure and for the assembly of the eIF-4F complex. The regulatory protein 4E-BP1, also referred to as PHAS-I, inhibits eIF-4E function. Phosphorylation of 4E-BP1 by S6 kinase p70, MAP kinases or PKCs causes the disassociation of 4E-BP1 from eIF-4E, promoting translation. A protein that is functionally related to 4E-BP1, designated 4E-BP2, also associates with eIF-4E.
desc-host-1:{21}(Product Details) Host	Mouse
prop-purification-1:{101}(Product Details) Purification	Synthetic phosphopeptide derived from human 4E-BP1 around the phosphorylation site of Threonine 37.
standard-form	phospho-T37
elisa-detection	Human, Mouse, Rat
desc-reactivity-1	FALSE
desc-molecular-weight-1	RUO
desc-alternative-names-1	Homo Sapiens (Human)

desc-applications-8	IHC
desc-cellular-localization-1	IHC1:50-1:200

desc-conjugate-1	Q13541
desc-constituent-1	Q13541
desc-intended-use-1	15 to 20 kDa

instructions-for-use	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.Specificity: p-4E-BP1 (T37) polyclonal antibody detects endogenous levels of 4E-BP1 protein only when phosphorylated at Thr37.
desc-net-weight-g-1	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
desc-positive-control-1	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

desc-recombinant-1	Datasheet
desc-recommended-dilution-1	https://www.bioworlde.com/pdf/BS4746.pdf
desc-regulatory-1	(pdf)

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SKU	Supplier No.	Size	Your price	Quantity
BHA11302674		50µl	$199.33		Add to Cart
BHA11302674		100µl	$314.89		Add to Cart

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