desc-alternative-names-1:(Description) Alternative Names
EGFR (Epidermal Growth Factor Receptor)
desc-antigen-1:(Description) Antigen
Erbb1|ERBB1|Errp|HER1|mENA|PIG61|Proto-oncogene c-ErbB-1|Receptor Tyrosine Protein Kinase|ErbB1|Urogastrone
desc-specificity-1:(Description) Specificity
Cell Surface
prop-purity-1:(Property) Purity
7p11.2
prop-storage-1:(Property) Storage
monoclonal
targ-uniprot-1
This MAb recognizes a protein of 170kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.
A431 cells. Placenta, Breast, Colon or Bladder cancer
elisa-detection
Human
desc-reactivity-1
FALSE
desc-molecular-weight-1
RUO
desc-applications-8
FACS, IF, IHC-F
desc-categories-1
(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
desc-cellular-localization-1
FACS0.5-1μg/million cellsIF1-2μg/mlIHC-F1-2μg/ml for 30 minutes at RT
desc-conjugate-1
P00533
desc-constituent-1
488293
desc-description-1:{15}(Description) Description
1956
desc-involvement-in-disease-1
200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1mg/ml.
desc-isotype-1:{29}(Description) Isotype
1.0mg/ml
instructions-for-use
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
desc-net-weight-g-1
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
No Description Available.
No Description Available.
Reviews of Anti-EGFR (Epidermal Growth Factor Receptor) Antibody BHA10200917