desc-alternative-names-1:(Description) Alternative Names
EGFR (Epidermal Growth Factor Receptor)
desc-antigen-1:(Description) Antigen
Erbb1|ERBB1|Errp|HER1|mENA|PIG61|Proto-oncogene c-ErbB-1|Receptor Tyrosine Protein Kinase|ErbB1|Urogastrone
desc-specificity-1:(Description) Specificity
Cell Surface
prop-purity-1:(Property) Purity
7p11.2
prop-storage-1:(Property) Storage
monoclonal
targ-uniprot-1
This antibody reacts with the extracellular domain of EGFR and blocks the EGF/TGF??induced activation. It also blocks tumor growth in vivo. It is excellent for purification of EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, βcellulin and epiregulin.
Affinity Purification (For coupling, order Ab without BSA); Blocks Ligand-induced Activation of EGFR; Inhibits Proliferation of A431 Cells (Order Ab without sodium azide); Arrests Tumor Growth in vivo (Order Ab without BSA &Azide); Optimal dilution for a specific application should be determined.
desc-cellular-localization-1
IP1-2 �g/500ug protein LysateFACS0.5-1μg/million cells in 0.1ml
desc-conjugate-1
P00533
desc-constituent-1
488293
desc-description-1:{15}(Description) Description
1956
desc-involvement-in-disease-1
200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA; azide at 1.0mg/ml.
desc-isotype-1:{29}(Description) Isotype
1.0mg/ml
instructions-for-use
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
desc-net-weight-g-1
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Reviews of Anti-EGFR (Epidermal Growth Factor Receptor) Antibody BHA10200882