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Home / Antibodies

Anti-Desmoglein-1 (DSG1) Antibody BHA10200766

SKU : BHA10200766

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NeoBiotechnologies, Inc.

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desc-alternative-names-1:(Description) Alternative Names	Desmoglein-1 (DSG1)
desc-antigen-1:(Description) Antigen	Cadherin family member 4\|CDHF4\|Desmoglein-1\|Desmosomal glycoprotein 1\|DG1\|DSG1\|EPKHE\|EPKHIA\|Pemphigus foliaceus antigen\|PPKS1
desc-specificity-1:(Description) Specificity	Cell Surface
prop-purity-1:(Property) Purity	18q12.1
prop-storage-1:(Property) Storage	monoclonal
targ-uniprot-1	Recognizes a protein of ~150kDa, identified as Desmoglein-1 (DSG1). Desmoglein-1 is a member of the desmosomal cadherin family. Desmosomes are intercellular adhering junctions that represent cell surface attachment sites for intermediate filament. Desmocollins and desmogleins are the main desmosomal transmembrane proteins. Desmogleins consist of Dsg1, Dsg2, Dsg3, and Dsg4 isoforms. Within the desmosome, the extracellular domain of desmoglein is essential for calcium dependent heterophilic binding to the desmocollins, whereas the intracellular domain is essential for binding to the desmosomal plaque protein, plakoglobin. Desmoglein 1 is synthesized exclusively in the suprabasal layers. Intact and functionally active desmoglein 1 is essential to epidermal integrity.
desc-host-1:{21}(Product Details) Host	Mouse
prop-purification-1:{101}(Product Details) Purification	Human desmoglein-1 intracellular domain (exact sequence is proprietary)
appl-tested-application-1:{73}(Product Details) Tested Application	IgG1 Kappa
desc-assay-procedure-3	A431 or A-375 cells. Skin
elisa-detection	Human
desc-reactivity-1	FALSE
desc-molecular-weight-1	RUO

desc-applications-8	FACS, IF, WB
desc-categories-1	Optimal dilution for a specific application should be determined.
desc-cellular-localization-1	FACS0.5-1μg/million cellsIF1-2μg/mlWB0.5-1.0μg/ml

desc-conjugate-1	Q02413
desc-constituent-1	2633
desc-description-1:{15}(Description) Description	1828

desc-involvement-in-disease-1	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA; azide at 1.0mg/ml.
desc-isotype-1:{29}(Description) Isotype	1.0mg/ml
instructions-for-use	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
desc-net-weight-g-1	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

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SKU	Supplier No.	Size	Your price	Quantity
BHA10200766		100µg	$393.20		Add to Cart

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