desc-alternative-names-1:(Description) Alternative Names
CD55 / Decay Accelerating Factor (DAF)
desc-antigen-1:(Description) Antigen
CD55|CD55 Cromer blood group system|Complement decay-accelerating factor|CROM|DAF|Daf-GPI|Decay Accelerating Factor for Complement|Decay accelerating factor GPI-form|Decay accelerating factor soluble-form|GPI-DAF
desc-specificity-1:(Description) Specificity
Cell Surface
prop-purity-1:(Property) Purity
1q32
prop-storage-1:(Property) Storage
monoclonal
targ-uniprot-1
Recognizes a single chain glycoprotein of 70kDa, identified as CD55 (also known as decay accelerating factor, DAF). CD55/DAF is widely expressed on cells throughout the body including leukocytes, erythrocytes, epithelium, endothelium, and fibroblasts. It is a Glycosyl phosphatidylinositol anchored (GPI-anchored) member of the membrane bound complement regulatory proteins that inhibit autologous complement cascade activation. It prevents the amplification steps of the complement cascade by interfering with the assembly of the C3-convertases, C4b2a and C3bBb, and the C5-convertase, C4b2a3b and C3bBb3b. CD55 also serves as receptor for CD97 and for echovirus and Coxsackie B virus. The MAb 143-30 can be used as marker for paroxysmal nocturnal hemoglobinuria (PNH).
Jurkat, HUT-78, K562, YT, U937, MG63, and human lymphocytes. Human lymph nodes and tonsils.
elisa-detection
Human
desc-reactivity-1
FALSE
desc-molecular-weight-1
RUO
desc-applications-8
FACS, IF, IHC-F
desc-categories-1
Optimal dilution for a specific application should be determined.
desc-cellular-localization-1
FACS0.5-1μg/million cells in 0.1mlIF0.5-1μg/mlIHC-F0.5-1μg/ml for 30 minutes at RT
desc-conjugate-1
P08174
desc-constituent-1
126517
desc-description-1:{15}(Description) Description
1604
desc-involvement-in-disease-1
200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA; azide at 1.0mg/ml.
desc-isotype-1:{29}(Description) Isotype
1.0mg/ml
instructions-for-use
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
desc-net-weight-g-1
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Reviews of Anti-CD55 / Decay Accelerating Factor (DAF) Antibody BHA10200693