desc-alternative-names-1:(Description) Alternative Names
CD50 / ICAM-3
desc-antigen-1:(Description) Antigen
ICAMR|Intercellular adhesion molecule 3 (ICAM3)
desc-specificity-1:(Description) Specificity
Cell Surface
prop-purity-1:(Property) Purity
19p13.2
prop-storage-1:(Property) Storage
monoclonal
targ-uniprot-1
Recognizes the D1 domain of an N-glycosylated glycoprotein of 120kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3 (Leucocyte Workshop VI). CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signaling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C. This MAb is excellent for staining of formalin/paraffin tissues.
Blocks binding of CD11a (LFA-1) to CD50 (ICAM-3) (Order Ab without Azide); (Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined.
desc-cellular-localization-1
FACS0.5-1μg/million cells in 0.1mlIF0.5-1μg/mlIHC-F0.5-1μg/ml for 30 minutes at RT
desc-conjugate-1
P32942
desc-constituent-1
354563
desc-description-1:{15}(Description) Description
3385
desc-involvement-in-disease-1
200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
desc-isotype-1:{29}(Description) Isotype
1.0mg/ml
instructions-for-use
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
desc-net-weight-g-1
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Reviews of Anti-CD50 / ICAM-3 Antibody BHA10202022