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Home / Antibodies

Anti-CD25 / IL2RA Antibody BHA10202375

SKU : BHA10202375

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NeoBiotechnologies, Inc.

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desc-alternative-names-1:(Description) Alternative Names	CD25 / IL2RA
desc-antigen-1:(Description) Antigen	IL2 Receptor alpha\|IL2R alpha chain\|IL2R\|IL2R subunit alpha IL2RA\|Interleukin-2 receptor subunit alpha\|Ly43\|p55\|p55 chain\|T Cell Growth Factor Receptor\|TAC antigen
desc-specificity-1:(Description) Specificity	Cell Surface
prop-purity-1:(Property) Purity	10p15-p14
prop-storage-1:(Property) Storage	monoclonal
targ-uniprot-1	Recognizes a protein of 55kDa, identified as CD25 (Workshop IV; Code A27). CD25 is expressed on activated T- and B-cells and activated monocytes/macrophages. With respect to lymphomas, CD25 is present on malignant cells of Hodgkinā€™s disease, HTLV-1+ adult T-cell leukemia, cutaneous T-cell lymphoma, and hair cell leukemia. Increased levels of soluble CD25 are observed in the leukemias/lymphomas and inflammatory/ autoimmune diseases. CD25 molecule alone appears to function as a low affinity receptor and associates with CD122 (IL-2R ļ� � chain, p75) and CD132 (common ļ� � chain) to form the high affinity IL-2 receptor complex. CD25 antibodies detect three epitope regions, A, B and C. This MAb recognizes the epitope B, which is located at residue 3-104 of CD25 and can effectively block IL-2 binding to CD25.
desc-host-1:{21}(Product Details) Host	Mouse
prop-purification-1:{101}(Product Details) Purification	Stimulated human leukocytes
appl-tested-application-1:{73}(Product Details) Tested Application	IgG1 Kappa
desc-assay-procedure-3	PHA-stimulated human lymphocytes. Human lymph nodes and tonsils.
elisa-detection	Human
desc-reactivity-1	FALSE
desc-molecular-weight-1	RUO

desc-applications-8	FACS, IF
desc-categories-1	Functional Studies (Order Ab without Azide); Optimal dilution for a specific application should be determined.
desc-cellular-localization-1	FACS0.5-1μg/million cells in 0.1mlIF0.5-1μg/ml

desc-conjugate-1	P01589
desc-constituent-1	231367
desc-description-1:{15}(Description) Description	3559

desc-involvement-in-disease-1	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA; azide at 1.0mg/ml.
desc-isotype-1:{29}(Description) Isotype	1.0mg/ml
instructions-for-use	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
desc-net-weight-g-1	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

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SKU	Supplier No.	Size	Your price	Quantity
BHA10202375		100µg	$393.20		Add to Cart

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