Enter to Debug Area Anti-CASP8 Antibody BHA11302613

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Anti-CASP8 Antibody BHA11302613

SKU : BHA11302613

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desc-alternative-names-1:(Description) Alternative Names	CASP8
desc-antigen-1:(Description) Antigen	Caspase-8\|Caspase8\|Caspase 8\|CASP-8\|Apoptotic cysteine protease\|Apoptotic protease Mch-5\|CAP4\|FADD-homologous ICE/ced-3-like protease\|FADD-like ICE\|FLICE\|ICE-like apoptotic protease 5\|MORT1-associated ced-3 homolog\|MACH\|Caspase-8 subunit p18\|Caspase-8 subunit p10\|CASP8\|MCH5
prop-purity-1:(Property) Purity	2q33.1
prop-storage-1:(Property) Storage	polyclonal
targ-uniprot-1	Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase 8 and Caspase 9. Activated initiator caspases then process effector caspases, such as Caspase 3 and Caspase 7, which in turn cause cell collapse.
desc-host-1:{21}(Product Details) Host	Mouse
prop-purification-1:{101}(Product Details) Purification	Synthetic phosphopeptide derived from human Caspase-8 around the phosphorylation site of Tyrosine 380.
standard-form	phospho-Y380
elisa-detection	Human, Mouse, Rat
desc-reactivity-1	FALSE
desc-molecular-weight-1	RUO
desc-alternative-names-1	Homo Sapiens (Human)

desc-applications-8	WB
desc-cellular-localization-1	WB1:500-1:1000

desc-conjugate-1	Q14790
desc-constituent-1	Q14790
desc-intended-use-1	38, 55 kDa

instructions-for-use	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.Specificity: p-Caspase 8 (Y380) polyclonal antibody detects endogenous levels of Caspase 8 protein only when phosphorylated at Tyr380.
desc-net-weight-g-1	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
desc-positive-control-1	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

desc-recombinant-1	Datasheet
desc-recommended-dilution-1	https://www.bioworlde.com/pdf/BS4662.pdf
desc-regulatory-1	(pdf)

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SKU	Supplier No.	Size	Your price	Quantity
BHA11302613		50µl	$199.33		Add to Cart
BHA11302613		100µl	$314.89		Add to Cart

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