Enter to Debug Area Anti-Blood Group Antigen A (CD173) Antibody BHA10201601

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Anti-Blood Group Antigen A (CD173) Antibody BHA10201601

SKU : BHA10201601

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NeoBiotechnologies, Inc.

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desc-alternative-names-1:(Description) Alternative Names	Blood Group Antigen A (CD173)
desc-antigen-1:(Description) Antigen	A transferase\|ABO\|B transferase\|CD173\|Fucosylglycoprotein 3-alpha-galactosyltransferase\|Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase\|Glycoprotein-fucosylgalactoside alpha-galactosyltransferase\|Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase\|Histo-blood group A transferase\|Histo-blood group B transferase
desc-specificity-1:(Description) Specificity	Cell Surface
prop-purity-1:(Property) Purity	9q34.2
prop-storage-1:(Property) Storage	monoclonal
targ-uniprot-1	This antibody recognizes human blood group A (monofucosyl and difucosyl A antigens with chain types 1, 2, 3, 4, 5, 6) and Forssmann antigen. It is also reactive with the immuno-dominant A trisaccharide. Blood group antigen expression in human colon cancer was studied by means of two monoclonal antibodies of broad anti-A (HE-14) and anti-type 3 and type 4 chain-based A and H (HE-10) specificity. These antigens were proved to re-appear in tumors of the distal colon, the HE-10 antibody reacting more frequently (9 out of 12 samples) than HE-14 (5 out of 12 samples) and frequently with supra-nuclear staining of the cytoplasm probably in those places of the Golgi apparatus where carbohydrate antigens are synthesized. This staining pattern is characteristic of HE-10 in normal colonic mucosa as well. With HE-14, staining was often absent in less differentiated tumors, while HE-10 did react in such tumors. In some cases, these two antibodies gave different staining patterns in parallel sections from the same tissue sample, primarily at the cellular level. Three out of 12 cases showed blood group antigen expression in the mucosa of the distal colon adjacent to the tumor only when HE-10 Ab was used.
desc-host-1:{21}(Product Details) Host	Mouse
prop-purification-1:{101}(Product Details) Purification	Mixture of erythrocytes of blood group A1 and glycoprotein fraction isolated from the saliva of secretors with blood group A
appl-tested-application-1:{73}(Product Details) Tested Application	IgM Kappa
desc-assay-procedure-3	KG1 cells or human colorectal carcinoma tissues.
elisa-detection	Human
desc-reactivity-1	FALSE
desc-molecular-weight-1	RUO

desc-applications-8	IF, IHC-F, AGG
desc-categories-1	(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined.
desc-cellular-localization-1	AGGIF0.5-1μg/mlIHC-F0.5-1.0μg/ml for 30 minutes at RT

desc-conjugate-1	P16442
desc-constituent-1	654423
desc-description-1:{15}(Description) Description	28

desc-involvement-in-disease-1	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA; azide at 1.0mg/ml.
desc-isotype-1:{29}(Description) Isotype	200µg/ml
instructions-for-use	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
desc-net-weight-g-1	Purified Ab with BSA and Azide at 200μg/ml

desc-recombinant-1	Download
desc-recommended-dilution-1	https://www.neobiotechnologies.com/html2pdf/pdf_create.php?cat_no=28-MSM4-P0
desc-regulatory-1	(pdf)

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SKU	Supplier No.	Size	Your price	Quantity
BHA10201601		20µg	$204.67		Add to Cart
BHA10201601		100µg	$393.20		Add to Cart

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