Enter to Debug Area Anti-BAD Antibody (BADS112-B9) APC BHA10600025

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Home / Primary Antibodies / Phospho Antibodies

Anti-BAD Antibody (BADS112-B9) APC BHA10600025

SKU : BHA10600025

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Abwiz Bio Inc.

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Mfr.No.	2249
desc-alternative-names-1:(Description) Alternative Names	Bad
prop-storage-1:(Property) Storage	monoclonal
prop-storage-buffer-1:(Property) Storage Buffer	APC
targ-uniprot-1	BAD is a distant member of the BCL-2 family, which regulate cell survival and apoptosis (1). Survival factors, such as IL-3, inhibit BAD's apoptotic activity by activating intracellular signaling pathways that result in the phosphorylation of BAD at Ser112 and Ser136 (1). S112/S136-phosphorylated phospho BAD binds to 14-3-3 proteins, sequestering phospho BAD in the cytosol and preventing association with Bcl-xL (1). Ser112 of BAD is phosphorylated both in vitro and in vivo by p90-RSK (2) and by mitochondria-anchored protein kinase A (3), while Ser136 of BAD is phosporylated by Akt to promote cell survival (4,5).
desc-host-1:{21}(Product Details) Host	Mouse
prop-purification-1:{101}(Product Details) Purification	A synthetic phospho-peptide corresponding to residues surrounding Ser112 of human phospho BAD
appl-tested-application-1:{73}(Product Details) Tested Application	IgG1 Lambda
standard-form	phospho-Ser112
elisa-detection	Mouse, Human
desc-sample-type-3	RUO

desc-applications-8	FACS

desc-formulation-1:{18}(Description) Formulation	BADS112-B9

desc-involvement-in-disease-1	1X PBS, 0.02% NaN3, 50% Glycerol, 0.1% BSA
desc-isotype-1:{29}(Description) Isotype	0.5mg/ml
biological-activity	1.0 - 0.1 µg/ml
desc-positive-control-1	-20ºC

desc-recombinant-1	Datasheet
desc-recommended-dilution-1	https://www.abwizbio.com/datasheet/datasheet.php?sku=2249
desc-regulatory-1	(pdf)

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SKU	Supplier No.	Size	Your price	Quantity
BHA10600025	2249	100Tests	$320.67		Add to Cart
BHA10600025	2249	10Tests	$120.67		Add to Cart

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