Enter to Debug Area Anti-ATM Antibody BHA11304727

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Anti-ATM Antibody BHA11304727

SKU : BHA11304727

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desc-alternative-names-1:(Description) Alternative Names	Atm
desc-antigen-1:(Description) Antigen	Serine-protein kinase ATM\|Ataxia telangiectasia mutated\|A-T mutated\|ATM
prop-purity-1:(Property) Purity	11q22.3
prop-storage-1:(Property) Storage	polyclonal
targ-uniprot-1	The phosphatidylinositol kinase (PIK) family members fall into two distinct subgroups. The first subgroup contains proteins such as the PI 3- and PI 4-kinases and the second group comprises the PIK-related kinases. The PIK-related kinases include Atm, DNA-PKCS and FRAP. These proteins have in common a region of homology at their carboxy-termini that is not present in the PI 3- and PI 4-kinases. The Atm gene is mutated in the autosomal recessive disorder ataxia telangiectasia (AT) that is characterized by cerebellar degeneration (ataxia) and the appearance of dilated blood vessels (telangiec-tases) in the conjunctivae of the eyes. AT cells are hypersensitive to ionizing radiation, impaired in mediating the inhibition of DNA synthesis and display delays in p53 induction.
desc-host-1:{21}(Product Details) Host	Mouse
prop-purification-1:{101}(Product Details) Purification	A synthetic peptide corresponding to residues in Human ATM around the phosphorylation site of ser1981.
standard-form	phospho-S1981
elisa-detection	Human, Mouse, Rat
desc-reactivity-1	FALSE
desc-molecular-weight-1	RUO
desc-alternative-names-1	Homo Sapiens (Human)

desc-applications-8	WB
desc-cellular-localization-1	WB1:500-1:1000

desc-conjugate-1	Q13315
desc-constituent-1	Q13315
desc-intended-use-1	370 kDa

instructions-for-use	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.Specificity: p-ATM (S1981) polyclonal antibody detects endogenous levels of ATM protein only when phosphorylated at ser1981.
desc-net-weight-g-1	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
desc-positive-control-1	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

desc-recombinant-1	Datasheet
desc-recommended-dilution-1	https://www.bioworlde.com/pdf/BS64019.pdf
desc-regulatory-1	(pdf)

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SKU	Supplier No.	Size	Your price	Quantity
BHA11304727		50µl	$199.33		Add to Cart
BHA11304727		100µl	$314.89		Add to Cart

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