Enter to Debug Area Anti-ARRB1 Antibody BHA11300032

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Anti-ARRB1 Antibody BHA11300032

SKU : BHA11300032

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desc-alternative-names-1:(Description) Alternative Names	ARRB1
desc-antigen-1:(Description) Antigen	ARB 1\|ARB1\|ARR 1\|ARR1\|ARRB 1\|ARRB1\|Arrestin 2\|Arrestin beta 1\|Arrestin beta-1\|Beta-arrestin-1\|Arrestin-β1\|Arrestin β1\|β-arrestin-1
prop-purity-1:(Property) Purity	11q13.4
prop-storage-1:(Property) Storage	polyclonal
targ-uniprot-1	Beta Arrestin 1 is a member of a family of proteins that are widely expressed but especially abundant in the central nervous system. Serving as an adaptor or scaffold molecule, beta Arrestin 1 is essential for mitogenic signaling. Beta Arrestin 1 has important roles in the cytoplasm and at the plasma membrane in the desensitization and internalization of G protein coupled receptors (GPCRs) and is increasingly appreciated to play an important role in the endocytosis and signaling of GPCRs. Beta Arrestin 1 in the cytosol is phosphorylated by ERK1 and 2 on serine 412 in a negative feedback mechanism and binds to the phosphorylated receptors at the plasma membrane.
desc-host-1:{21}(Product Details) Host	Mouse
prop-purification-1:{101}(Product Details) Purification	Synthetic phosphopeptide derived from human Arrestin-β-1 around the phosphorylation site of Serine 412.
standard-form	phospho-S412
elisa-detection	Human, Mouse, Rat
desc-reactivity-1	FALSE
desc-molecular-weight-1	RUO
desc-alternative-names-1	Homo Sapiens (Human)

desc-applications-8	WB
desc-cellular-localization-1	WB1:500-1:1000

desc-conjugate-1	P49407
desc-constituent-1	P49407
desc-intended-use-1	50 kDa

instructions-for-use	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.Specificity: p-Arrestin-β-1 (S412) polyclonal antibody detects endogenous levels of Arrestin-β-1 protein only when phosphorylated at Ser412.
desc-net-weight-g-1	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
desc-positive-control-1	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

desc-recombinant-1	Datasheet
desc-recommended-dilution-1	https://www.bioworlde.com/pdf/AP0240.pdf
desc-regulatory-1	(pdf)

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SKU	Supplier No.	Size	Your price	Quantity
BHA11300032		50µl	$199.33		Add to Cart
BHA11300032		100µl	$314.89		Add to Cart

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