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Home / Antibodies

Anti-AMACR / p504S Antibody BHA10201273

SKU : BHA10201273

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NeoBiotechnologies, Inc.

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desc-alternative-names-1:(Description) Alternative Names	AMACR / p504S
desc-antigen-1:(Description) Antigen	Alpha-methylacyl-CoA Racemase\|CBAS4\|Da1-8\|Macr1\|RACE\|RM
desc-specificity-1:(Description) Specificity	Cytoplasmic
prop-purity-1:(Property) Purity	5p13.3
prop-storage-1:(Property) Storage	polyclonal
targ-uniprot-1	This antibody recognizes a protein of 54kDa, which is identified as AMACR, also known as p504S. It is an enzyme that is involved in bile acid biosynthesis and Ī �-oxidation of branched-chain fatty acids. AMACR is essential in lipid metabolism. It is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands. AMACR is expressed in normal liver (hepatocytes), kidney (tubular epithelial cells) and gall bladder (epithelial cells). Expression has also been found in lung (bronchial epithelial cells) and colon (colonic surface epithelium). AMACR expression can also be found in hepatocellular carcinoma and kidney carcinoma. Past studies have also shown that AMACR is expressed in various colon carcinomas (well, moderately and poorly differentiated) and over expressed in prostate carcinoma.
desc-host-1:{21}(Product Details) Host	Mouse
prop-purification-1:{101}(Product Details) Purification	A synthetic peptide from human AMACR protein
appl-tested-application-1:{73}(Product Details) Tested Application	IgG
desc-assay-procedure-3	HEK cells or Prostate Adenocarcinoma
elisa-detection	Human
desc-reactivity-1	FALSE
desc-molecular-weight-1	RUO

desc-applications-8	IHC-F
desc-categories-1	(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined.
desc-cellular-localization-1	IHC-F1:50-1:100 for 30-60 minutes at RT

desc-conjugate-1	Q9UHK6
desc-constituent-1	508343
desc-description-1:{15}(Description) Description	23600

desc-involvement-in-disease-1	200μg/ml of Ab purified from rabbit anti-serum by Protein A. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA at 1.0mg/ml.
desc-isotype-1:{29}(Description) Isotype	200µg/ml
instructions-for-use	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
desc-net-weight-g-1	Purified Ab with BSA and Azide at 200μg/ml

desc-recombinant-1	Download
desc-recommended-dilution-1	https://www.neobiotechnologies.com/html2pdf/pdf_create.php?cat_no=23600-RBP2-P0
desc-regulatory-1	(pdf)

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SKU	Supplier No.	Size	Your price	Quantity
BHA10201273		20µg	$204.67		Add to Cart

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