Anti-AKT3/AKT2/AKT1 Antibody BHA11308937

desc-alternative-names-1:(Description) Alternative Names	AKT3/AKT2/AKT1
desc-antigen-1:(Description) Antigen	RAC-alpha serine/threonine-protein kinase\|Protein kinase B\|PKB\|Protein kinase B alpha\|PKB alpha\|Proto-oncogene c-Akt\|RAC-PK-alpha\|AKT1\|PKB\|RAC\|PKBα\|RAC-beta serine/threonine-protein kinase\|Protein kinase Akt-2\|Protein kinase B beta\|PKB beta\|RAC-PK-beta\|AKT2\|PKBβ\|RAC-gamma serine/threonine-protein kinase\|Protein kinase Akt-3\|Protein kinase B gamma\|PKB gamma\|RAC-PK-gamma\|STK-2\|AKT3\|PKBG\|PKBγ
prop-storage-1:(Property) Storage	monoclonal
targ-uniprot-1	AKT, also known as protein kinase B (PKB), is a 57 kDa serine/threonine protein kinase. There are three mammalian isoforms of Akt: AKT1 (PKB alpha), AKT2 (PKB beta) and AKT3 (PKB gamma) with AKT2 and AKT3 being approximately 82% identical with the AKT1 isoform. Each isoform has a pleckstrin homology (PH) domain, a kinase domain and a carboxy terminal regulatory domain. AKT was originally cloned from the retrovirus AKT8, and is a key regulator of many signal transduction pathways. Its tight control over cell proliferation and cell viability are manifold; overexpression or inappropriate activation of AKT has been seen in many types of cancer.
desc-host-1:{21}(Product Details) Host	Mouse
prop-purification-1:{101}(Product Details) Purification	Recombinant antibody.
standard-form	phospho-Ser473
elisa-detection	Human, Mouse
desc-reactivity-1	TRUE
desc-molecular-weight-1	RUO

desc-applications-8	ICC/IF, IHC, WB
desc-cellular-localization-1	WB1:1,000-1:2,000ICC/IF1:50-1:200IHC1:50-1:200

instructions-for-use	Product: Recombinant Rabbit Monoclonal Antibody. 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.Specificity: This antibody detects endogenous levels of AKT1 only when phosphorylated at Ser473. This antibody also recognizes AKT2 and AKT3 when phosphorylated at the corresponding residues.
desc-net-weight-g-1	Protein A affinity purified
desc-positive-control-1	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.